Treatment of Peyronie’s Disease
Based on the Stage of the Disease
Under the supervision of Professor Alexander Knigavko
- Conservative Methods
- Collagenase+ Protocol
- Microsurgery
An Affordable Alternative to Xiaflex (USA)
Symptoms develop gradually — it is in the early stage that the disease responds best to treatment
Treatment of Peyronie’s Disease:
from pain syndrome
to complex forms of deformity
Under the supervision of Professor Alexander Knigavko
Modern conservative methods,
Collagenase+ protocol, microsurgery,
stage-based treatment selection
An affordable alternative to Xiaflex treatment in the USA
UAE · Oman · Moldova · Ukraine
Symptoms develop gradually — it is in the early stage that the disease responds best to treatment
Formation of a fibrous plaque is the key stage of Peyronie’s disease. It is during this period that the condition is still amenable to correction, and there is an opportunity to prevent further progression of the disease.
Our Approach to the Treatment of Peyronie’s Disease
The treatment protocol for Peyronie’s disease is selected based on the stage of the condition
Patients seek medical care at different stages of the disease — from the active inflammatory phase to stages with pronounced deformities and calcification of the fibrous plaque.
Determining the stage of the condition is essential for developing an individualized treatment plan and selecting the most effective approach for each patient
In the active phase, when the fibrous plaque is still forming and inflammatory activity persists, the main goal of treatment is to target the pathological tissue
In the absence of timely treatment at the stage of fibrous plaque formation, the disease may progress and transition into a phase of persistent deformity, plaque calcification, and pronounced functional impairment
In such cases, conservative treatment methods become insufficiently effective, and surgical correction using modern microsurgical techniques is required
Surgical treatment is performed using the full range of modern microsurgical techniques, with an emphasis on preserving erectile function
Individualized Treatment Protocol Based on Disease Stage
The treatment strategy is selected strictly based on the phase of Peyronie’s disease, as well as the structure and activity of the fibrous plaque
Professor Knigavko’s Proprietary Protocol
A proprietary clinical strategy combining modern injection techniques,
biostimulation, rehabilitation, and microsurgery
Early Intervention in the Active Phase of the Disease
Focus on treatment during the plaque formation stage to halt the fibrotic process and reduce the risk of deformity
Proprietary Collagenase+ Protocol
An affordable and effective alternative to Xiaflex: biocompatible collagenase combined with PRP, stem cells, and exosomes
Treatment of All Stages of Peyronie’s Disease
From the active inflammatory phase to severe calcified forms and complex deformities
Modern Microsurgical Techniques
A full range of surgical techniques for correcting severe forms of the disease with maximum preservation of function
Biological Support After Treatment and Surgery
Rehabilitation protocols aimed at reducing the risk of recurrence and preserving erectile function
International Clinical Experience
Clinical practice and treatment of patients at leading medical centers in Dubai, Muscat, Kyiv, and Moldova
Global Standards Without Traveling to the USA
Treatment based on international protocols used in the USA, Europe, and Asia
Telemedicine and Remote Support
Online consultations, treatment monitoring, and patient support at all stages
Personal Physician Supervision at Every Stage
From the initial consultation to the completion of treatment and rehabilitation
There are no universal solutions in the treatment of Peyronie’s disease. Only an accurate assessment of the stage of the condition and an individualized selection of treatment strategy lead to results
Each patient undergoes a diagnostic evaluation, after which a personalized plan is developed — from conservative treatment in the active phase to surgical correction for complex deformities
This approach allows not only to target the fibrous plaque but also to preserve function, reduce the risk of disease progression, and avoid unnecessary interventions
Professor Knigavko’s approach is based on many years of clinical experience, modern injection and microsurgical techniques, as well as consistent patient support at all stages of treatment